New review just published. Main-chain water-soluble polyphosphoesters: Multi-functional polymers as degradable PEG-alternatives for biomedical applications.
Polyphosphoesters (PPEs) are a class of (bio)degradable polymers with high chemical versatility and functionality, currently discussed as a potential alternative to poly(ethylene glycol) (PEG). Several PPE candidates have proven their biocompatibility in vitro in terms of cytocompatibility, “stealth effect”, degradability and some promising in vivo results.
Congratulations to Nicola Di Fidio, Ph.D. student of our Doctoral School in Chemistry and Materials Science, and third-place winner of the national contest for young innovators "Falling Walls Lab Italy 2020", organized by the University of Milan-Bicocca. The jury, composed of experts from the academic, research and business world, awarded Nicola's research project which aims to create an innovative biorefinery model for the conversion of agro-industrial wastes into biofuels and bioproducts through Green Chemistry approaches, in the perspective of the new model of circular economy.
Congratulations to our Ph.D. student Andrea Cesari for his scientific publication entitled “Interaction of natural flavonoid eriocitrin with β-cyclodextrin and hydroxypropyl-β-cyclodextrin: an NMR and molecular dynamics investigation” in “New Journal of Chemistry”. Many studies have focused on improving water solubility, stability and shelf-life of natural flavonoid. To overcome this problems, β-cyclodextrin and its derivatives are interesting candidates.
Here we present this review work, based on a scrupulous and important bibliographic reaserch concerning glycoconjugated metal complexes used for tumor therapy and diagnosis.
Tumor cells display augmented requests for carbohydrates and, in particular, for glucose in order to sustain their high proliferation rate, which causes an increased glycolytic process (Warburg effect).
