Dottorando nel contest nazionale per innovatori

Dottorando nel contest nazionale per innovatori

L'idea innovativa del Dott. Nicola Di Fidio, allievo della Scuola di Dottorato DSCM, è stata selezionata tra i 10 progetti per la tappa italiana del contest internazionale "Falling Walls Lab...

DSCM accreditato per il 36° ciclo

DSCM accreditato per il 36° ciclo

Il Dottorato in Scienze Chimiche e dei Materiali (DSCM) è stato accreditato per il 36° ciclo (2020-2023), ottenendo anche la qualifica di “Dottorato innovativo - Internazionale” grazie alla presenza di...

From individual fellowships to the horizon - A short course on project writing on the European platform

From individual fellowships to the horizon - A short course on project writing on the European platform

From individual fellowships to the horizon - A short course on project writing on the European platform  by Dr. Martina Calamusa, Prof. Benedetta Mennucci, Prof. Andrea Pucci, Prof. Gaetano Angelici ...

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ratiometric intracellular phWe present a fluorescent pH biosensor based on a conjugated coumarin-triazine scaffold that is excitable in the visible range, shows pseudo-linear ratiometric response over more than 6 pH units with a single fluorogenic unit, and allows imaging of the whole endo-lysosomal pH landscape of living cells with a single acquisition. The probe can discriminate, on the basis of intracellular acidity, between physiologic and tumor cells, being potentially suitable in perspective as diagnostic tool.

mechanochromic lldpe filmsNew article just published by the Smart Polymer Group: "Mechanochromic LLDPE Films Doped with NIR Reflective Paliogen Black" (C. Micheletti, P. Minei, Prof. G. Ruggeri, Prof. A. Pucci). The work shows the self-diagnostic properties of P-black/LLDPE film as a new solution to detect deformations through optical and thermal outputs.
Here the abstract of the article.
The perylene bisimide derivative Paliogen Black (P-black) is proposed as a new chromogenic probe that shows visible (Vis) and near-infrared (NIR) responses after mechanical solicitations of host linear low-density polyethylene (LLDPE) films.

review crisprcas 2020Congratulations to our Ph.D. students Andrea Bonini, Noemi Poma and Federico Vivaldi from the Chemistry Lab for Analytical Technologies and Sensors (CATS), for their recent review entitled "Advances in biosensing: The CRISPR/Cas system as a new powerful tool for the detection of nucleic acids". This year, the Nobel Prize in Chemistry was awarded for the use of the CRISPR/Cas system in molecular biology. Recently, the coupling of the CRISPR/Cas system with isothermal amplification methods is fostering the development of innovative optical and electrochemical Point of Care (POC) devices and seems to offer unprecedented possibilities.

ppes alternativeNew review just published. Main-chain water-soluble polyphosphoesters: Multi-functional polymers as degradable PEG-alternatives for biomedical applications.
Polyphosphoesters (PPEs) are a class of (bio)degradable polymers with high chemical versatility and functionality, currently discussed as a potential alternative to poly(ethylene glycol) (PEG). Several PPE candidates have proven their biocompatibility in vitro in terms of cytocompatibility, “stealth effect”, degradability and some promising in vivo results.

falling walls difidioCongratulations to Nicola Di Fidio, Ph.D. student of our Doctoral School in Chemistry and Materials Science, and third-place winner of the national contest for young innovators "Falling Walls Lab Italy 2020", organized by the University of Milan-Bicocca. The jury, composed of experts from the academic, research and business world, awarded Nicola's research project which aims to create an innovative biorefinery model for the conversion of agro-industrial wastes into biofuels and bioproducts through Green Chemistry approaches, in the perspective of the new model of circular economy.

eriocitrin cyclodextrin complexesCongratulations to our Ph.D. student Andrea Cesari for his scientific publication entitled “Interaction of natural flavonoid eriocitrin with β-cyclodextrin and hydroxypropyl-β-cyclodextrin: an NMR and molecular dynamics investigation” in “New Journal of Chemistry”. Many studies have focused on improving water solubility, stability and shelf-life of natural flavonoid. To overcome this problems, β-cyclodextrin and its derivatives are interesting candidates.

Dipartimento di Chimica
e Chimica Industriale
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Via G. Moruzzi, 13 - Pisa, Italy
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Doctoral School in Chemistry
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