Congratulations to our PhD student Carlo Marotta for his scientific publication entitled “An overview of recent advancements in anticancer Pt(IV) prodrugs: new smart drug combinations, activation and delivery strategies ” in Inorganica Chimica Acta. In this article, the most recent advancements made in the field of anticancer Pt(IV) complexes were reviewed. First, have been described Pt(IV) complexes functionalized with molecules that could increase the anticancer activity of the entire complex.
Phytochromes are ubiquitous photoreceptors responsible for sensing light in plants, fungi and bacteria. Their photoactivation is initiated by the photoisomerization of an embedded chromophore, triggering large conformational changes in the protein. Despite numerous experimental and computational studies, a lot of questions remain unanswered: what happens to the chromophore just after light absorption? How does the environment affect the entire activation process?
Congratulations to our PhD student Adele Ferretti for her publication entitled "A model iron gall ink: an indepth study of ageing processes involving gallic acid". Iron gall inks have been among the most used writing materials, thus representing an important element of historical and artistic heritage of our society. Conversely, many conservation issues arise from the presence of iron gall inks in manuscripts and drawings, as a conspicuous fading of the text and paper acidification and degradation.
Congratulations to our Ph.D. student Elisabetta Rosadoni for her publication "Ligandless Palladium-Catalyzed Direct C-5 Arylation of Azoles Promoted by Benzoic Acid in Anisole" on Molecules. In this paper we report a selective C-5 arylation procedure involving anisole as an EHS green reaction solvent. In addition, the beneficial role of benzoic acid in this reaction as an additive is also highlighted. The palladium-catalyzed direct arylation of azoles with (hetero)aryl halides is nowadays one of the most versatile and efficient procedures for the selective synthesis of heterobiaryls.
